Pharmacology — Key differences for NEET MDS
Esters = metabolized by plasma pseudocholinesterase = procaine. Amides = metabolized in liver = lidocaine. Lidocaine = gold standard LA = 2 percent most common. Onset determined by pKa = lower pKa faster onset. Duration determined by protein binding = higher binding longer duration. Articaine = unique hybrid amide with ester group. Prilocaine = least toxic amide. Bupivacaine = most cardiotoxic.
📖 Read full notes →Warfarin plus NSAIDs = increased bleeding risk. Erythromycin plus Warfarin = enhanced anticoagulation. Epinephrine plus TCAs = hypertensive crisis risk. Metronidazole plus Alcohol = disulfiram-like reaction. Aspirin plus Warfarin = enhanced bleeding. Ketoconazole plus Midazolam = enhanced sedation. Ciprofloxacin plus Theophylline = toxicity.
📖 Read full notes →NEET MDS frequently tests the ability to differentiate between related topics. Understanding the key differences between LA Pharmacology and Drug Interactions in Pharmacology is crucial for scoring well. Questions may test diagnostic features, treatment approaches, or characteristic findings.