Pharmacology — Key differences for NEET MDS
Esters = metabolized by plasma pseudocholinesterase = procaine. Amides = metabolized in liver = lidocaine. Lidocaine = gold standard LA = 2 percent most common. Onset determined by pKa = lower pKa faster onset. Duration determined by protein binding = higher binding longer duration. Articaine = unique hybrid amide with ester group. Prilocaine = least toxic amide. Bupivacaine = most cardiotoxic.
📖 Read full notes →Ibuprofen = most commonly prescribed NSAID in dentistry. Ketorolac = most potent NSAID for acute pain. COX-2 selective = Celecoxib Etoricoxib = less GI side effects. Diclofenac = most prescribed NSAID worldwide. Paracetamol = safest in pregnancy = not anti-inflammatory. Tramadol = synthetic opioid = dual mechanism. Aspirin = irreversible COX inhibitor = antiplatelet 7-10 days.
📖 Read full notes →NEET MDS frequently tests the ability to differentiate between related topics. Understanding the key differences between LA Pharmacology and NSAIDs & Opioids in Pharmacology is crucial for scoring well. Questions may test diagnostic features, treatment approaches, or characteristic findings.