Lymph Node Pathology & Lymphomas

Hodgkin lymphoma. Reed-Sternberg ('owl-eye') cells characterise Hodgkin lymphoma.

Burkitt lymphoma. Burkitt lymphoma shows the starry-sky pattern (macrophages among tumour cells).

Non-Hodgkin. Non-Hodgkin lymphomas are more common at extranodal/oral sites.

⭐ High-Yield Facts for Exam

Hodgkin lymphoma — diagnostic Reed-Sternberg cells ('owl-eye'); orderly spread; better prognosis stage-for-stage.
Non-Hodgkin lymphoma (NHL) — more common in the oral cavity/extranodal sites.
Burkitt lymphoma — 'starry-sky' histology, c-myc translocation, EBV association; African (jaw) and sporadic forms.
MALT lymphoma — mucosa-associated lymphoid tissue.
HIV increases NHL risk.

Persistent firm, non-tender lymphadenopathy warrants evaluation/biopsy.

Reed-Sternberg = Hodgkin; NHL more common orally; Burkitt = starry sky + c-myc + EBV.

Q1. Reed-Sternberg cells are diagnostic of:

A. Burkitt lymphoma

B. Hodgkin lymphoma

C. MALT lymphoma

D. Myeloma

Show Answer

✅ Answer: B

Reed-Sternberg ('owl-eye') cells characterise Hodgkin lymphoma.

Q2. A 'starry-sky' appearance is seen in:

A. Hodgkin lymphoma

B. Burkitt lymphoma

C. Pleomorphic adenoma

D. Ameloblastoma

Show Answer

✅ Answer: B

Burkitt lymphoma shows the starry-sky pattern (macrophages among tumour cells).

Q3. Which lymphoma is more common in the oral cavity?

A. Hodgkin

B. Non-Hodgkin

C. Both equal

D. Neither

Show Answer

✅ Answer: B

Non-Hodgkin lymphomas are more common at extranodal/oral sites.

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