💡 p53 = most commonly mutated tumor suppressor. Ki-67 = proliferation marker. EGFR = overexpressed in OSCC. HPV 16/18 = oropharyngeal cancer. EBV = nasopharyngeal + Burkitt. bcl-2 = anti-apoptotic.

💡 Type I = IgE (anaphylaxis). Type II = IgG/IgM (Pemphigus). Type III = immune complexes (SLE). Type IV = T-cell (contact dermatitis). ANA = screening. Anti-dsDNA = specific for SLE.

💡 Hodgkin = Reed-Sternberg cells (owl-eye). Non-Hodgkin = more common orally. Burkitt = starry sky, EBV, c-myc. MALT lymphoma = mucosa-associated. HIV = increased NHL risk.

💡 Fibrous dysplasia = ground glass, GNAS mutation. Ossifying fibroma = well-demarcated. Cherubism = bilateral mandible, SH3BP2, 'eyes raised to heaven'. Paget = cotton wool, elevated ALP.

💡 Fibroma = most common benign oral tumor. Pyogenic granuloma = pregnancy tumor. Peripheral giant cell granuloma = only on gingiva. Kaposi sarcoma = HHV-8. Hemangioma = most common in infancy.